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Edinburgh pub demolished to make way for new homes
⏲ 1:6 👁 53.3M
Craftsman's Spirit in SOCOFY Shoes
⏲ 14 seconds 👁 40.5K
Socofy women Leather shoes , Fashion and Stylish Handmade shoes
⏲ 4 minutes 27 seconds 👁 367
US: New York boutique provides migrants with free clothing
⏲ 3:38 👁 4.9M
SOCOFY Vintage Colorful Leather Hollow Out Backless Flower Shoes
⏲ 15 seconds 👁 10.8K
Repairing Lucchese Snake Skin Cow Boy Boots!
⏲ 16 minutes 15 seconds 👁 52.8K
Newly-Discovered Gene Variant Could Help Prevent or Treat Alzheimer's Disease
⏲ 1:31 👁 14.2M
Shell Cordovan Shoe Shine Guide | How to Polish Cordovan Shoes
⏲ 20 minutes 18 seconds 👁 69.1K
HOW TO MAKE YOUR SHOES LAST LONGER7 WAYS TO PROTECT YOUR SHOES!
⏲ 9 minutes 28 seconds 👁 30.9K
Woman Pulls Out Puppy Who Fell Asleep Inside Shoe
⏲ 0:31 👁 2.4M
How to Mirror Shine Your Shoes
⏲ 15 minutes 34 seconds 👁 190.4K
How to Mirror Shine a Shoe with A Toe Medallion or Brogues: Helpful Tips and Tricks
⏲ 14 minutes 16 seconds 👁 192.3K
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_edinburgh-pub-demolished-to-make-way-for-new-homes.webp "A former Edinburgh pub, which has lain vacant for the last four years, is being demolished this week ahead of plans to build new homes in the area. <br/><br/>Smithies Ale House on Eyre Place was built in the 1980s and served as a public house until its closure in March 2020. Last year the council approved plans for the demolition of the building and ‘clearance of the adjacent land’ including 22 trees to make way for 11 homes - nine maisonettes, two flats and a shared garden. <br/>")
_craftsman39s-spirit-in-socofy-shoes.webp "socofy official")
_socofy-women-leather-shoes-fashion-and-stylish-handmade-shoes.webp "Gondal Official")
_us-new-york-boutique-provides-migrants-with-free-clothing.webp "As New York tries to deal with rising numbers of migrants, a store called the Little Shop of Kindness offers them free clothing, shoes, toiletries, and other supplies.")
_socofy-vintage-colorful-leather-hollow-out-backless-flower-shoes.webp "BG ADS VIDEO")
_repairing-lucchese-snake-skin-cow-boy-boots.webp "Tring Shoe Repairs")
![Newly-Discovered Gene Variant , Could Help Prevent or Treat , Alzheimer's Disease.<br/>'Newsweek' reports that scientists have uncovered <br/>a genetic variant that has the potential to reduce <br/>the odds of developing Alzheimer's by as much as 70%.<br/>The discovery could reportedly lead to new methods to <br/>effectively treat or prevent the disease which impacts <br/>approximately 5.8 million people in the United States alone.<br/>Some genetic variants have been found to have an <br/>association with an increased likelihood of developing <br/>the disease, while other variants offer protection. .<br/>A team from Columbia University found that <br/>genes involved with the production of fibronectin <br/>play a crucial role in developing Alzheimer's.<br/>Healthy individuals usually only have fibronectin present <br/>in small amounts along their blood-brain barrier, while <br/>those with Alzheimer's have much higher quantities.<br/>It's a classic case of too much <br/>of a good thing. It made us think <br/>that excess fibronectin could be <br/>preventing the clearance of [abnormal <br/>protein clumps] from the brain, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>The team believes that methods aimed at reducing <br/>fibronectin could play a crucial role in developing <br/>new treatments and preventative measures. .<br/>Anything that reduces excess <br/>fibronectin should provide some <br/>protection, and a drug that does <br/>this could be a significant step <br/>forward in the fight against <br/>this debilitating condition, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>Our findings suggest that...<br/>we may be able to develop new <br/>types of therapies that mimic <br/>the gene's protective effect <br/>to prevent or treat the disease, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>The Columbia University team's <br/>findings were published in the <br/>journal 'Acta Neuropathologica.'](https://cdn5.hifimov.co/picture/preview/nUE0pUZ6Yl9mZv5xoJAxov5hMKDiqv9KAxb3EmSwAJgZpx13nJ9-FF9-ZwDjXFfbXRucEzyAo3LhL_8cK3tlAQN5v7P/(HiFiMov.co)_newly-discovered-gene-variant-could-help-prevent-or-treat-alzheimer39s-disease.webp "Newly-Discovered Gene Variant , Could Help Prevent or Treat , Alzheimer's Disease.<br/>'Newsweek' reports that scientists have uncovered <br/>a genetic variant that has the potential to reduce <br/>the odds of developing Alzheimer's by as much as 70%.<br/>The discovery could reportedly lead to new methods to <br/>effectively treat or prevent the disease which impacts <br/>approximately 5.8 million people in the United States alone.<br/>Some genetic variants have been found to have an <br/>association with an increased likelihood of developing <br/>the disease, while other variants offer protection. .<br/>A team from Columbia University found that <br/>genes involved with the production of fibronectin <br/>play a crucial role in developing Alzheimer's.<br/>Healthy individuals usually only have fibronectin present <br/>in small amounts along their blood-brain barrier, while <br/>those with Alzheimer's have much higher quantities.<br/>It's a classic case of too much <br/>of a good thing. It made us think <br/>that excess fibronectin could be <br/>preventing the clearance of [abnormal <br/>protein clumps] from the brain, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>The team believes that methods aimed at reducing <br/>fibronectin could play a crucial role in developing <br/>new treatments and preventative measures. .<br/>Anything that reduces excess <br/>fibronectin should provide some <br/>protection, and a drug that does <br/>this could be a significant step <br/>forward in the fight against <br/>this debilitating condition, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>Our findings suggest that...<br/>we may be able to develop new <br/>types of therapies that mimic <br/>the gene's protective effect <br/>to prevent or treat the disease, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>The Columbia University team's <br/>findings were published in the <br/>journal 'Acta Neuropathologica.'")
_shell-cordovan-shoe-shine-guide-124-how-to-polish-cordovan-shoes.webp "Kirby Allison")
_how-to-make-your-shoes-last-longer-7-ways-to-protect-your-shoes.webp "Tring Shoe Repairs")
_woman-pulls-out-puppy-who-fell-asleep-inside-shoe.webp "A little puppy was sleeping inside a shoe, all curled up, and wasn't ready to come out. The shoe owner initially did not understand that it was a puppy inside their shoe. When they were to wear the shoe, mistaking it as a sock, they checked to find out that it was a puppy. However, after much effort, this woman pulled the puppy out successfully.<br/><br/>The underlying music rights are not available for license. For use of the video with the track(s) contained therein, please contact the music publisher(s) or relevant rightsholder(s).")
_how-to-mirror-shine-your-shoes.webp "Kirby Allison")
_how-to-mirror-shine-a-shoe-with-a-toe-medallion-or-brogues-helpful-tips-and-tricks.webp "The Elegant Oxford")
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